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Apoprotein A-V is a Potential Target For Coronary Artery Disease

Triglyceride lowering lipoprotein lipase enzyme and genetic Low Density Lipoprotein-C variants have been associated  with reduced risk of coronary artery disease. It is found that Apoprotein-V variants strongly affect serum triglyceride levels. It is suggested that ApoA-V and LDL-C variants reduce triglyceride levels and prevent Coronary Artery Disease risk. If this is proven by further studies, Apo A-V will be a potential therapeutic target for CAD prevention.

References: Dorina Ibi  et al; Journal of Lipid Research 2022, March 9.:100193